ОНТОГЕНЕЗ DROSOPHILA MELANOGASTER ЯК МІШЕНЬ НІКОТИНОВОЇ ТОКСИЧНОСТІ. ПОВІДОМЛЕННЯ І
DOI:
https://doi.org/10.18524/2077-1746.2025.1(56).337318Ключові слова:
Drosophila melanogaster, нікобустер, нікотин, розвиток, політенні хромосоми, плодючість, фітнес, токсичний стресАнотація
У роботі досліджено вплив нікобустера для електронних сигарет на розвиток Drosophila melanogaster при пероральному введенні. Показано, що нікотин зумовлює дозозалежну затримку метаморфозу, зниження виживаності та плодючості. Водночас виявлено підвищення ступеня політенізації ядер клітин слинних залоз личинок, що може свідчити про активацію компенсаторних механізмів у відповідь на токсичний стрес. Отримані результати вказують на личинку як критичну мішень дії нікотину та підкреслюють мультифакторний характер його впливу на розвиток D. melanogaster.
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